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Professor Martins Emeje, PhD

I am a Pharmaceutical Research Scientist with the National Institute for Pharmaceutical Research and Development (NIPRD), Idu, Abuja, Nigeria. I have over the years created an understanding of the molecular behavior of polymeric materials and the compaction properties of pharmaceutical powders, excipients and active pharmaceutical ingredients including the physico-mechanical properties of drug formulations using these substances. Having conducted several research projects in herbal pharmacotherapy, herbal formulation, compaction characteristics of pharmaceutical powders, and excipient characterization, my expertise focuses on the development of solid oral dose formulations for immediate- and sustained- release applications and the physical properties of polymer-polymer and polymer-drug interactions. I am particularly interested in molecular solid state characterization and possible application of natural polymers in Nanomedicine for the targeted delivery of more challenging conventional drugs such as peptides/proteins, insoluble bioactive agents, and other macro molecules.

I have successfully utilized a semi synthetic polymer (sodium carboxy methyl cellulose) of different molecular sizes, alone and in combination with some hydrophobic polymers (ethylcellulose, cellulose acetate phthalate, and Eudragit-L 100) to deliver theophylline and chlorpheniramine maleate. I have also looked at the compaction characteristics of some polymers, alone (ethylcellulose and starch) and in combination with some additives (mannitol, sorbitol, and PEGs). Moreover, I have recently concluded the first multi-scale characterization of about 25 African biomass. To characterize the materials, high-tech and sophisticated equipments such as the scanning electron microscope, X-ray powder diffractometer, thermo-gravimetric analyzer, differential scanning calorimeter, FTIR, and NMR spectrophotometers etc were used. The materials were successfully utilized in the design of novel drug targeting systems, including colonic delivery of albendazole pellets, nanoparticles of zidovudine, and drop pills of diclofenac-K.

I have presented about 45 abstracts at international conferences and many at local conferences. I have collaborated with many established researchers across the globe and have published more than 100 research papers in international peer-reviewed journals. Apart from this core academic competency, I am also knowledgeable in the Intellectual Property Rights (IPR). I have attended training and capacity building sessions on IPR in the United Kingdom. I coordinate IPR matters at my Institution. I also serve as the liaison officer and I am responsible for coordinating research collaborations between my Institution and the pharmaceutical industries in Nigeria.

These trainings and expertise that I have acquired over the years have enabled me to formulate therapeutic targets for different human diseases. I was among the only 5 candidates from across the globe, whose proposals won the 2010 JNCASR-CCSTDS Fellowship to India, and among the only 2 Nigerians selected for the prestigious CV Raman Postdoctoral Fellowship in India during 2011, following a competitive proposal. My current research interest is in the areas of Nanotechnology, chemical and biological synthesis of functionalized nanomaterials and their polymer bionanocomposites as well as nanoparticles from chemically synthesized natural polysaccharides. I undertake research on interaction of drugs, biomedically relevant metal ions, and functionalized nanoparticles with live cell as well as whole animal and their application in targeted drug delivery with specific interest in malaria, tuberculosis, and cancer.


Education

University of Nigeria, Nsukka,

Dept. of Pharmaceutical Technology and Industrial Pharmacy

PhD, June 2009

 

 

 

University of Nigeria, Nsukka,

Dept. of Pharmaceutical Technology and Industrial Pharmacy

Mpharm., August 2005

 

 

 

Ahmadu Bello University, Zaria

Faculty of Pharmaceutical Sciences

Bpharm., December 1998

 

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Tel: +2348037035738

Research Interests:

·        Novel drug delivery

.     Nanotechnology 

·        Interaction of water with polymers

·        Polymer - Polymer interactions

·        Polymer - Drug interactions

·        Physical characterization of novel excipients

·        Formulation of herbal APIs

·       Compaction characteristics of pharmaceutical powders

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